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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2603fa09af12f69fad423f389dadfbcc4668c2adb1faf6c517404ba3d6a07edd' 
  AND token = 'OLkaW8LAnA7ua7ZECM6UscRuG9hM3fRf08L5Cv6fZgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}